Bandyopadhyay acted in sixty-six films in his acting career spanning six decades. He worked with Satyajit Ray in films like Mahanagar (1964), Kapurush (1965), Sonar Kella (1974) and Joi Baba Felunath (1979).
He had also acted in recent Hindi films like Barfi! and Parineeta.
Bandyopadhyay won the National Award for Best Supporting Actor in 2005 and Banga Vibhushan by the Government of West Bengal in 2011.